Aurein 2.6

Aurein 2.6 is an antibiotic antimicrobial peptide. Aurein 2.6 is active against Gram-positive bacterial (MIC: 25, 25, 30, 25, 30 μM for M. luteus, S. aureus, S. epidermis, S. mutans, B. subtilis) [1][2].

Product Specifications

CAS Number

[302343-10-8]

UNSPSC

12352209

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aurein-2-6.html

Solubility

10 mM in DMSO

Smiles

CC(C)C[C@@H](C(N)=O)NC([C@H](CO)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CN)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C77H133N19O19

Molecular Weight

1629.00

References & Citations

[1]Rozek T, et al. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2. Eur J Biochem. 2000 Sep;267 (17) :5330-41.|[2]Dennison SR, et al. PEGylation enhances the antibacterial and therapeutic potential of amphibian host defence peptides. Biochim Biophys Acta Biomembr. 2022 Feb 1;1864 (1) :183806.