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DMRT1 Mouse Monoclonal Antibody [Clone ID: LBI4E12]

Product Specifications

Background

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain) . The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Synonyms

CT154; DMT1

Gene Name

Homo sapiens doublesex and mab-3 related transcription factor 1 (DMRT1), transcript variant 1, mRNA.

Gene ID

1761

UniProt

Q9Y5R6

Conjugation

Unconjugated

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome, Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

DMRT1

Overview

Carrier-free (BSA/glycerol-free) DMRT1 mouse monoclonal antibody, clone LBI4E12

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1761

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y5R6

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