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MRZ 2-514

MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.

Product Specifications

CAS Number

202808-11-5

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/MRZ_2-514.html

Purity

95.08

Solubility

10 mM in DMSO

Smiles

O=C1NNC(C2=C1C=C3C=C(Br)C=CC3=[N+]2[O-])=O

Molecular Formula

C11H6BrN3O3

Molecular Weight

308.09

Precautions

H302, H315, H319

References & Citations

[1]Parsons CG, et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. Journal of Pharmacology and Experimental Therapeutics (1997), 283 (3), 1264-1275

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Available Sizes

Frequently Asked Questions

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