HM43239
Product Specifications
CAS Number
2569527-64-4
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CC1CN (CC (C) N1) CC2=CC (=CC (=C2) NC3=NC=C (Cl) C (=N3) C4=C[NH]C5=C4C=CC (=C5) C) C6CC6
Molecular Formula
C29H33ClN6
Additionnal Information
HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s’ of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2928142-01 20 µg
Recombinant Mouse B-cell receptor-associated protein 29 (Bcap29)
Sign In for Pricing
View Details orb2928142-02 100 µg
Recombinant Mouse B-cell receptor-associated protein 29 (Bcap29)
Sign In for Pricing
View Details 