Indisulam
Product Specifications
CAS Number
165668-41-7
Synonyms
E7070
Target
Carbonic Anhydrase
Applications
Metabolism
Smiles
N[S] (=O) (=O) C1=CC=C (C=C1) [S] (=O) (=O) NC2=C3[NH]C=C (Cl) C3=CC=C2
Molecular Formula
C14H12ClN3O4S2
Additionnal Information
Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.
Storage Conditions
3 years -20°C powder
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