Apostatin-1 (Apt-1)
Product Specifications
CAS Number
2559703-06-7
Target
TRADD
Applications
Apoptosis
Smiles
CN1CCN=C1SC (C (=O) NC2CCCCCC2) C3=CC=CC=C3
Molecular Formula
C19H27N3OS
Additionnal Information
Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N) . Apostatin-1 inhibits bortezomib-induced apoptosis and RIPK1-dependent apoptosis (RDA) with an IC50 of about 1 μM.
Storage Conditions
3 years -20°C powder
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