Recombinant MLH1 Monoclonal Antibody
Product Specifications
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Abbreviation
MLH1
UniProt
P40692
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human MLH1
Target
COCA 2; COCA2; DNA mismatch repair protein Mlh1; FCC 2; FCC2; hMLH 1; hMLH1; HNPCC 2; HNPCC; HNPCC2; MGC5172; MLH 1; MLH1; MLH1; MutL homolog 1 (E. coli) ; MutL homolog 1; MutL homolog 1 colon cancer nonpolyposis type 2; MutL homolog 1; colon cancer; nonpolyposis type 2 (E. coli) ; MutL protein homolog 1; MutL; E. coli; homolog of;1
Clonality
Monoclonal
Clone
R02-2E8
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000; IF 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
85kDa
Observed Molecular Weight
85kDa
Isotype
IgG
Available Sizes
Documents
Frequently Asked Questions
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