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G10 (STING agonist-1)

Product Specifications

CAS Number

702662-50-8

Target

IFN

Applications

Immunology & Inflammation

Smiles

C1C (=O) N (C2=C (S1) C=CC (=C2) C (=O) NCC3=CC=CO3) CC4=C (C=CC=C4Cl) F

Molecular Formula

C21H16ClFN2O3S

Additionnal Information

G10 (STING agonist-1) is a novel human-specific STING agonist that triggers IFN regulatory factor 3 (IRF3) / type I interferon (IFN) -associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM.

Storage Conditions

3 years -20°C powder

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