Naporafenib (LXH254)
Product Specifications
CAS Number
1800398-38-2
Target
Raf
Applications
MAPK
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC (=NC=C2) C (F) (F) F) C3=CC (=NC (=C3) OCCO) N4CCOCC4
Molecular Formula
C25H25F3N4O4
Additionnal Information
Naporafenib (LXH254) is a type II ATP-competitive inhibitor that inhibits both B- and CRAF kinase activities at picomolar concentrations with a high degree of selectivity against a panel of 456 human kinases and in cell-based assays.
Storage Conditions
3 years -20°C powder
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