G-CSF
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and mouse G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
Product Specifications
Synonyms
CSF3; GCSF; CSF3OS; C17orf33
NCBI Gene ID
1440
UniProt
P09919
Accession Number
NP_000750.1
Accession Number mRNA
NM_000759
Chromosomal Location
17q11.2-q12
Reactivity
Human
Cross Reactivity
Monkey, Mouse, Pig, Human, Plant
Sequence
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Length
174
Form
Lyophilized
Molecular Weight
18.7 kDa
Host or Source
E. coli
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