INCB3344
Product Specifications
CAS Number
1262238-11-8
Target
CCR
Applications
GPCR & G Protein
Smiles
CCOC1CN (CC1NC (=O) CNC (=O) C2=CC (=CC=C2) C (F) (F) F) C3CCC (O) (CC3) C4=CC=C5OCOC5=C4
Molecular Formula
C29H34F3N3O6
Additionnal Information
INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
Storage Conditions
3 years -20°C powder
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