Uprosertib (GSK2141795)
Product Specifications
CAS Number
1047634-65-0
Synonyms
GSK795
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CN1C (=C (C=N1) Cl) C2=C (OC (=C2) C (=O) NC (CC3=CC (=C (C=C3) F) F) CN) Cl
Molecular Formula
C18H16Cl2F2N4O2
Additionnal Information
Uprosertib (GSK2141795, GSK795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
Storage Conditions
2 years -80 in solvent
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