Resmetirom (MGL-3196)
Product Specifications
CAS Number
920509-32-6
Synonyms
VIA-3196
Target
THR
Applications
Endocrinology & Hormones
Smiles
CC (C) C1=CC (=NNC1=O) OC2=C (C=C (C=C2Cl) N3C (=O) NC (=O) C (=N3) C#N) Cl
Molecular Formula
C17H12Cl2N6O4
Additionnal Information
Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β (THR-β) agonist with an EC50 of 0.21 μM, shows 28-fold selective for THR-β over THR-α in a functional assay.
Storage Conditions
3 years -20°C powder
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