Antitumor agent-59
Antitumor agent-59 (Compound 13b) is a potent antitumor agent. Antitumor agent-59 effectively inhibits the proliferation and migration of HCT116 cells. Antitumor agent-59 induces HCT116 cell apoptosis and arrests the cell cycle at the G2/M phase[1].
Product Specifications
CAS Number
[2409952-04-9]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-59.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C(C(N3CCC4=C(C13)NC5=CC=C(C=C54)OC(CCCC(OC6=CC=C7NC8=C(C7=C6)CCN9C(C%10=C(N(C89)C)C=CC(F)=C%10)=O)=O)=O)=O)C=C(C=C2)F
Molecular Formula
C43H36F2N6O6
Molecular Weight
770.78
References & Citations
[1]Liang H, et al. Discovery of novel bis-evodiamine derivatives with potent antitumor activity. Bioorg Med Chem. 2022 Jul 1;65:116793.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146409/Antitumor-agent-59-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146409/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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