MPP+ iodide
Product Specifications
CAS Number
36913-39-0
Synonyms
N-Methyl-4-Phenylpyridinium Iodide
Target
Autophagy
Applications
Autophagy
Smiles
[I-].C[N+]1=CC=C (C=C1) C2=CC=CC=C2
Molecular Formula
C12H12IN
Additionnal Information
MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons.
Storage Conditions
3 years-20°C (in the dark) powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
158114 96 Tests
Sulfatase 1 (SULF1) BioAssayTM ECL ELISA Kit (Human)
Sign In for Pricing
View Details 
302488-Biotin 100 µL
HNRNPA1L2 (Heterogeneous Nuclear Ribonucleoprotein A1-like 2, hnRNP A1-like 2, hnRNP core Protein A1-like 2, HNRNPA1L2, HNRNPA1L) (Biotin) discontinued
Sign In for Pricing
View Details 
MBS7147755 Inquire
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KIN6 Polyclonal Antibody
Sign In for Pricing
View Details