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Baricitinib phosphate

Product Specifications

CAS Number

1187595-84-1

Synonyms

INCB-028050 phosphate, LY-3009104 phosphate

Target

JAK

Applications

Angiogenesis

Smiles

CCS (=O) (=O) N1CC (C1) (CC#N) N2C=C (C=N2) C3=C4C=CNC4=NC=N3.OP (=O) (O) O

Molecular Formula

C16H20N7O6PS

Additionnal Information

Baricitinib phosphate (INCB-028050, LY-3009104) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research for COVID-19.

Storage Conditions

3 years -20°C powder

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