Rolapitant
Product Specifications
CAS Number
552292-08-7
Synonyms
SCH-619734
Target
Neurokinin Receptor
Applications
Neuronal Signaling
Smiles
CC (C1=CC (=CC (=C1) C (F) (F) F) C (F) (F) F) OCC2 (CCC3 (CCC (=O) N3) CN2) C4=CC=CC=C4
Molecular Formula
C25H26F6N2O2
Additionnal Information
Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS064123-20ug 20 µg
ETL (ADGRL4) (NM_022159) Human Over-expression Lysate
Sign In for Pricing
View Details 422065-01 100 mg
((2S,4R) -2- (Chloromethyl) -2- (2,4-dichlorophenyl) -1,3-dioxolan-4-yl) methyl 4-Methylbenzenesulfonate
Sign In for Pricing
View Details 
422065-02 250 mg
((2S,4R) -2- (Chloromethyl) -2- (2,4-dichlorophenyl) -1,3-dioxolan-4-yl) methyl 4-Methylbenzenesulfonate
Sign In for Pricing
View Details 