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Sarsasapogenin

Product Specifications

CAS Number

126-19-2

Synonyms

Parigenin

Target

ROS

Applications

NF-κB

Smiles

CC1CCC2 (C (C3C (O2) CC4C3 (CCC5C4CCC6C5 (CCC (C6) O) C) C) C) OC1

Molecular Formula

C27H44O3

Additionnal Information

Sarsasapogenin (SAR, Parigenin) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.

Storage Conditions

2 years -80 in solvent

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