FcRn & B2M Heterodimer Recombinant Protein
Product Specifications
Background
FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51 (alpha chain) and Beta-2-microglobulin (Beta chain) . The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk, Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog (FcRn) and beta-2-microglobulin (B2M) .
NCBI Gene ID
14132
Swiss Prot
Q61559, P01887
Accession Number
Q61559, P01887
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-590
Calculated Molecular Weight
44.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Fc receptor, IgG, alpha chain transporter
NCBI Organism
Mus musculus
Other Product Names
IgG receptor FcRn, Neonatal Fc receptor, FCRN
Species
Mouse
Physical Properties
Lyophilized
CAS Number
9000-83-3
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