Demethyl-Coclaurine
Product Specifications
CAS Number
5843-65-2
Synonyms
Higenamine, Norcoclaurine
Target
Adrenergic Receptor
Applications
Neuronal Signaling
Smiles
OC1=CC=C (CC2NCCC3=CC (=C (O) C=C23) O) C=C1
Molecular Formula
C16H17NO3
Additionnal Information
Demethyl-Coclaurine (Higenamine, Norcoclaurine), the key component of the Chinese herb aconite root, is a beta-2 adrenergic receptor (β2-AR) agonist. Demethyl-Coclaurine stimulates AKT phosphorylation and requires PI3K activation for the anti-apoptotic effect in cardiomyocytes.
Storage Conditions
3 years -20°C powder
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