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TAK-715

Product Specifications

CAS Number

303162-79-0

Target

P38 MAPK

Applications

MAPK

Smiles

CCC1=NC (=C (S1) C2=CC (=NC=C2) NC (=O) C3=CC=CC=C3) C4=CC=CC (=C4) C

Molecular Formula

C24H21N3OS

Additionnal Information

TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.

Storage Conditions

2 years -80 in solvent

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