BAY 11-7082
Product Specifications
CAS Number
19542-67-7
Synonyms
BAY 11-7821
Target
Apoptosis related
Applications
Apoptosis
Smiles
CC1=CC=C (C=C1) S (=O) (=O) C=CC#N
Molecular Formula
C10H9NO2S
Additionnal Information
BAY 11-7082 (BAY 11-7821) is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50 of 0.19 μM and 0.96 μM, respectively. BAY 11-7082 induces apoptosis and S phase arrest in gastric cancer cells.
Storage Conditions
2 years -80 in solvent
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