TPCA-1
Product Specifications
CAS Number
507475-17-4
Synonyms
GW683965
Target
IκB/IKK
Applications
NF-κB
Smiles
C1=CC (=CC=C1C2=CC (=C (S2) NC (=O) N) C (=O) N) F
Molecular Formula
C12H10FN3O2S
Additionnal Information
TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1. TPCA-1 is also an inhibitor of STAT3 and enhances apoptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
302284-ML490 100 µL
BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-like 3, B-ATF-3, 21kD Small Nuclear Factor isolated from T-Cells, Jun Dimerization Protein p21SNFT, BATF3, SNFT) (MaxLight 490) discontinued
Sign In for Pricing
View Details orb3088920 200 µL
Pseudomonas sp. HMSC065H01 PILC Rabbit Polyclonal Antibody (Carrier-free)
Sign In for Pricing
View Details