Dabrafenib
Product Specifications
CAS Number
1195765-45-7
Synonyms
GSK2118436, GSK2118436A
Target
Raf
Applications
MAPK
Smiles
CC (C) (C) C1=NC (=C (S1) C2=NC (=NC=C2) N) C3=C (C (=CC=C3) NS (=O) (=O) C4=C (C=CC=C4F) F) F
Molecular Formula
C23H20F3N5O2S2
Additionnal Information
Dabrafenib is a mutant BRAFV600E specific inhibitor with IC50 of 0.7 nM in cell-free assays, with 7- and 9-fold less potency against B-Raf (wt) and c-Raf, respectively.
Storage Conditions
2 years -80 in solvent
More Discoveries
Explore Other Products
Browse additional items from our catalog
43064-100μl 100 µL
Anti-Bcl-2 (Phospho-Thr56) Antibody (43064) - 100μl
Sign In for Pricing
View Details 
FE59050 0.1 Kg
Ethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Sign In for Pricing
View Details LS003854-100ug 100 µg
Cytokeratin 6B (KRT6B) (NM_005555) Human Over-expression Lysate
Sign In for Pricing
View Details