PKI-402

Product Specifications

CAS Number

1173204-81-3

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CCN1C2=C (C (=NC (=N2) C3=CC=C (C=C3) NC (=O) NC4=CC=C (C=C4) C (=O) N5CCN (CC5) C) N6CCOCC6) N=N1

Molecular Formula

C29H34N10O3

Additionnal Information

PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R.

Storage Conditions

2 years -80 in solvent

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