PRMT5-IN-33
Product Specifications
Target
Apoptosis|||Histone Methyltransferase
Related Pathways
Apoptosis|||Chromatin/Epigenetic
Bioactivity
PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.
Molecular Formula
C25H24BrN5O3S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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