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Torkinib (PP242)

Product Specifications

CAS Number

1092351-67-1

Target

Autophagy

Applications

Autophagy

Smiles

CC (C) N1C2=NC=NC (=C2C (=N1) C3=CC4=C (N3) C=CC (=C4) O) N

Molecular Formula

C16H16N6O

Additionnal Information

Torkinib (PP242) is a selective mTOR inhibitor with IC50 of 8 nM in cell-free assays; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively. Torkinib (PP242) induces mitophagy and apoptosis.

Storage Conditions

2 years -80 in solvent

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