BIX 02189
Product Specifications
CAS Number
1094614-85-3
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN (C) CC1=CC (=CC=C1) N=C (C2=CC=CC=C2) C3=C (NC4=C3C=CC (=C4) C (=O) N (C) C) O
Molecular Formula
C27H28N4O2
Additionnal Information
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
Storage Conditions
2 years -80 in solvent
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