BX-912
Product Specifications
CAS Number
702674-56-4
Smiles
C1CCN (C1) C (=O) NC2=CC=CC (=C2) NC3=NC=C (C (=N3) NCCC4=CN=CN4) Br
Molecular Formula
C20H23BrN8O
Additionnal Information
BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold.
Storage Conditions
2 years -80 in solvent
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