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MSH4 Polyclonal Antibody

This is a MSH4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

Synonyms

MSH4

Gene ID

4438

Swiss Prot

O15457

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein of human MSH4

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

39kDa/117kDa

Observed Molecular Weight

117kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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