OSI-930
Product Specifications
CAS Number
728033-96-3
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
C1=CC=C2C (=C1) C (=CC=N2) CNC3=C (SC=C3) C (=O) NC4=CC=C (C=C4) OC (F) (F) F
Molecular Formula
C22H16F3N3O2S
Additionnal Information
OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
Storage Conditions
2 years -80 in solvent
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