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Everolimus

Product Specifications

CAS Number

159351-69-6

Synonyms

RAD001, SDZ-RAD

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) OCCO) C) C) O) OC) C) C) C) OC

Molecular Formula

C53H83NO14

Additionnal Information

Everolimus is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.

Storage Conditions

2 years -80 in solvent

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