Astemizole
Product Specifications
CAS Number
68844-77-9
Synonyms
R 43512
Target
Histamine Receptor
Applications
Neuronal Signaling
Smiles
COC1=CC=C (C=C1) CCN2CCC (CC2) NC3=NC4=CC=CC=C4N3CC5=CC=C (C=C5) F
Molecular Formula
C28H31FN4O
Additionnal Information
Astemizole (R 43512) is a histamine H1-receptor antagonist with IC50 of 4.7 nM. Astemizole is also a potent inhibitor of ether à-go-go 1 (Eag1) and Eag-related gene (Erg) potassium channels. Astemizole has antineoplastic and antipruritic effects.
Storage Conditions
3 years -20°C powder
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