Recombinant human TALDO1 protein

TALDO1 is a key enzyme of the non-oxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This protein transfers a dihydroxyacetone group from donor compounds (fructose 6-phosphate or sedoheptulose 7-phosphate) to aldehyde acceptor compounds. It is expressed at selectively high levels in oligodendrocytes of the brain. Deficiency of TALDO1 causes accumulation of erythritol, D-arabitol, and ribitol. Recombinant human TALDO1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Transaldolase 1, TAL, TAL-H, TALDOR, TALH, TALDO1, Transaldolase 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.7 kDa (357aa) confirmed by MALDI-TOF

Additionnal Information

TALDO1, Transaldolase 1, TAL, TAL-H, TALDOR, TALH, TALDO1, Transaldolase 1, ATGP0666-10 µg, ATGP0666-20 µg, ATGP0666-50 µg, ATGP0666-100 µg, ATGP0666-250 µg, ATGP0666-500 µg, ATGP0666-1 mg, ATGP0666-10, ATGP0666-20, ATGP0666-50, ATGP0666-100, ATGP0666-250, ATGP0666-500, ATGP0666-1

References & Citations

Sprenger GA., et al. (2009) Int J Biochem Cell Biol. 41 (7) :1482-94.; ; Saudubray JM., et al (2006) J Pediatr. 149 (5) :713-7.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_006746

Uniprot Accession Number

P37837

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK