ICA-110381
Product Specifications
CAS Number
325457-99-6
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
C1=CC (=CC=C1C (=O) NC2=CN=C (C=C2) Cl) Cl
Molecular Formula
C12H8Cl2N2O
Additionnal Information
ICA 110381 (Compound 16) is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. ICA 110381 exhibits KCNQ2/Q3 agonist activity with EC50 of 0.38 μM and KCNQ1 antagonist activity with IC50 of 15 μM, respectively.
Storage Conditions
3 years -20°C powder
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