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Anti-Hu deltaNp73 Purified

The p53 family of proteins includes three members, p53, p63, and p73. The protein p73 is encoded by TP73 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp73) or absence (deltaNp73) of an N-terminal transactivation domain. Investigations have been hampered by a lack of well characterized antibodies that are specific for p73 and do not cross-react with the related p53 and p63 proteins, as well as a lack of antibodies that specifically recognize either the TAp73 or deltaNp73 variants. We are introducing now such a set of antibodies.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

KLH-coupled synthetic peptide MLYVGDPARHLATC

Target Antigen

DeltaNp73

Clone

DNp73-1.1

Applications

WB, ICC, IP

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody DNp73-1.1 recognizes human deltaNp73; target epitope is MLYVGDPARHLAT.

Applications Notes

Western blotting: Recommended dilution: 1 μg/ml

Isotype

Mouse IgG1

Frequently Asked Questions

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