GEM144
Product Specifications
CAS Number
2487526-28-1
Synonyms
Flezurafenibum
Target
HDAC
Applications
DNA Damage/DNA Repair
Additionnal Information
GEM144 is a potent and orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC11 . It exhibits potent antiproliferative activity in vitro and antitumor efficacy in vivo by inducing p53 acetylation, p21 activation, G1/S cell cycle arrest, and apoptosis.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PI 3 Kinase p55 gamma [SR44-06] Antibody](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
224902-01 50 µL
PCBP2 (Alpha CP2, Alpha-CP2, alphaCP-2, Cbp, CTBP, Heterogeneous Nuclear Ribonucleoprotein E2, Heterogenous Nuclear Ribonucleoprotein E2, hnRNP E2, hnRNP-E2, HNRNPE2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, PCBP2, PCBP2_HUMAN, poly (rC) Binding Protein 2, Poly (rC) -Binding Protein 2, Putative heterogeneous Nuclear Ribonucleoprotein X, rCBinding Protein 2, ) discontinued
Sign In for Pricing
View Details 224902-02 100 µL
PCBP2 (Alpha CP2, Alpha-CP2, alphaCP-2, Cbp, CTBP, Heterogeneous Nuclear Ribonucleoprotein E2, Heterogenous Nuclear Ribonucleoprotein E2, hnRNP E2, hnRNP-E2, HNRNPE2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, PCBP2, PCBP2_HUMAN, poly (rC) Binding Protein 2, Poly (rC) -Binding Protein 2, Putative heterogeneous Nuclear Ribonucleoprotein X, rCBinding Protein 2, ) discontinued
Sign In for Pricing
View Details