What is the catalog number for OPB-171775?

The catalog number for OPB-171775 is C03287-5mg.

What sizes are available for OPB-171775?

OPB-171775 is available in the following size(s): 5 mg.

Is OPB-171775 in stock?

OPB-171775 is currently made to order / not held in immediate stock. Contact us for lead time.

OPB-171775

Product Specifications

CAS Number

2131210-15-4

Target

PDE

Applications

Metabolism

Molecular Formula

C15H18F2N2O3

Additionnal Information

OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) . This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST) .