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C2 Depleted Sera

Normal human serum depleted of complement C2 protein.

Product Specifications

Background

Normal human serum depleted of complement C2 protein by immunoaffinity chromatography. The product is tested for the absence of C2 by functional assays for classical pathway activity and for C2 protein by double immunodiffusion. The absence of C2 also prevents complement activation by the lectin pathway but the alternative pathway will still activate on appropriate surfaces.

Source

Normal human serum

Applications

See citations and technical data sheet for application info.

Concentration

>50 mg protein/mL (refer to CoA for lot specific concentration) .

Purity

No C2 detectable by immunodiffusion.

Activity

>80% versus normal human serum standard when reconstituted.

Form

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 μm filtered.

Storage Conditions

Store at -70°C or below. Minimize freeze/thaw cycles.

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