Compound 401
Product Specifications
CAS Number
168425-64-7
Target
DNA-PK
Applications
PI3K/Akt/mTOR
Smiles
C1COCCN1C2=CC (=O) N3C=CC4=CC=CC=C4C3=N2
Molecular Formula
C16H15N3O2
Additionnal Information
Compound 401 is a synthetic inhibitor of DNA-PK (IC50=0.28 μM) and mTOR (IC50=5.3 μM) . It has no inhibition on p110α/p85α PI3K (>100 μM) and blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.
Storage Conditions
3 years -20°C powder
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