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Fruquintinib

Product Specifications

CAS Number

1194506-26-7

Synonyms

HMPL-013

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C2=C (O1) C=C (C=C2) OC3=NC=NC4=CC (=C (C=C43) OC) OC) C (=O) NC

Molecular Formula

C21H19N3O5

Additionnal Information

Fruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.

Storage Conditions

3 years -20°C powder

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