Ipatasertib (GDC-0068)
Product Specifications
CAS Number
1001264-89-6
Synonyms
RG7440
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CC1CC (C2=C1C (=NC=N2) N3CCN (CC3) C (=O) C (CNC (C) C) C4=CC=C (C=C4) Cl) O
Molecular Formula
C24H32ClN5O2
Additionnal Information
Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.
Storage Conditions
2 years -80 in solvent
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