Fluorescent Kallikrein Substrate

<strong>Fluorescent Kallikrein Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2011313_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 612.7 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Kallikrein Substrate, fluorescent Z-Phe-Arg-AMC_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Gruba N, Rachubik P, Piwkowska A, Lesner A. Analysis of urinary kallikrein-related peptidase 13 for monitoring bladder cancer Biomarkers. 2021 Dec;26(8):770-779._x000D_ 2: Andrade D, Assis DM, Santos JA, Alves FM, Hirata IY, Araujo MS, Blaber SI, Blaber M, Juliano MA, Juliano L. Substrate specificity of kallikrein-related peptidase 13 activated by salts or glycosaminoglycans and a search for natural substrate candidates Biochimie. 2011 Oct;93(10):1701-9._x000D_ 3: Cloutier SM, Chagas JR, Mach JP, Gygi CM, Leisinger HJ, Deperthes D. Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology Eur J Biochem. 2002 Jun;269(11):2747-54._x000D_ 4: Lara-Marquez ML, Christiansen SC, Riedl MA, Herschbach J, Zuraw BL. Threshold-stimulated kallikrein activity distinguishes bradykinin- from histamine-mediated angioedema Clin Exp Allergy. 2018 Nov;48(11):1429-1438._x000D_ 5: Oliva ML, Andrade SA, Batista IF, Sampaio MU, Juliano M, Fritz H, Auerswald EA, Sampaio CA. Human plasma kallikrein and tissue kallikrein binding to a substrate based on the reactive site of a factor Xa inhibitor isolated from Bauhinia ungulata seeds Immunopharmacology. 1999 Dec;45(1-3):145-9._x000D_ 6: Angelo PF, Lima AR, Alves FM, Blaber SI, Scarisbrick IA, Blaber M, Juliano L, Juliano MA. Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects J Biol Chem. 2006 Feb 10;281(6):3116-26._x000D_ 7: Andrade D, Assis DM, Lima AR, Oliveira JR, Araujo MS, Blaber SI, Blaber M, Juliano MA, Juliano L. Substrate specificity and inhibition of human kallikrein-related peptidase 3 (KLK3 or PSA) activated with sodium citrate and glycosaminoglycans Arch Biochem Biophys. 2010 Jun 1;498(1):74-82._x000D_ 8: Zhu YD, Peng J, Jiang LP, Zhu JJ. Fluorescent immunosensor based on CuS nanoparticles for sensitive detection of cancer biomarker Analyst. 2014 Feb 7;139(3):649-55._x000D_ 9: Pimenta DC, Oliveira A, Juliano MA, Juliano L. Substrate specificity of human cathepsin D using internally quenched fluorescent peptides derived from reactive site loop of kallistatin Biochim Biophys Acta. 2001 Jan 12;1544(1-2):113-22._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25003700">10: Breger JC, Sapsford KE, Ganek J, Susumu K, Stewart MH, Medintz IL. Detecting kallikrein proteolytic activity with peptide-quantum dot nanosensors ACS Appl Mater Interfaces. 2014 Jul 23;6(14):11529-35. </a>_x000D_ _x000D_ <strong>Products Related to Fluorescent Kallikrein Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>