Mipomersen
Product Specifications
CAS Number
1000120-98-8
Synonyms
ISIS 301012 free base
Target
HCV
Applications
Microbiology
Additionnal Information
Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B-100 (apoB-100) that causes selective degradation of apoB-100 mRNA, thereby inhibiting protein translation. This leads to reductions in low-density lipoprotein cholesterol (LDL-C) and other apoB-containing lipoprotein levels. Mipomersen is used as an adjunct treatment for homozygous familial hypercholesterolemia (FH) .
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
298420 100 µg
KEAP1, Recombinant, Human, aa321-609, His-Tag (Kelch-Like ECH-Associated Protein, INRF2, KIAA0132, KLHL19)
Sign In for Pricing
View Details 
029480 100 µg
FOXO1, phosphorylated (Thr24) (FKHR, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead In Rhabdomyosarcoma, FOXO1A)
Sign In for Pricing
View Details APS0389-01 200 µL
Fluor647-conjugated Polyclonal Rabbit Anti-Rat IgG (H+L) Secondary Antibody
Sign In for Pricing
View Details APS0389-02 500 µL
Fluor647-conjugated Polyclonal Rabbit Anti-Rat IgG (H+L) Secondary Antibody
Sign In for Pricing
View Details