Amosulalol
Amosulalol (YM 09538) is an orally active and dual inhibitor of α1/β1-Adrenergic Receptor. Amosulalol exhibits antihypertensive activity via α1-Adrenergic Receptor inhibition. Amosulalol decreases reflexogenic increases in heart rate and plasma renin activity (PRA) via β1-Adrenergic Receptor inhibition in spontaneously hypertensive rats (SHR) [1].
Product Specifications
CAS Number
85320-68-9
Product Name Alternative
YM 09538
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/amosulalol.html
Purity
98.69
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC(C(O)CNCCOC2=C(C=CC=C2)OC)=CC=C1C)=O
Molecular Formula
C18H24N2O5S
Molecular Weight
380.46
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor; β adrenergic receptor
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