DCLK1-IN-1
Product Specifications
CAS Number
2222635-15-4
Target
Serine/threonin kinase
Applications
Cell Cycle
Smiles
COC1=C (NC2=NC=C3N (CC (F) (F) F) C (=O) C4=CC=CC=C4N (C) C3=N2) C=CC (=C1) N5CCN (C) CC5
Molecular Formula
C26H28F3N7O2
Additionnal Information
DCLK1-IN-1 is a selective, in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1) domain that binds to DCLK1 and DCLK2 with IC50 of 9.5 nM and 31 nM, respectively. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases with IC50 of 57.2 nM and 103 nM in kinase assay, respectively.
Storage Conditions
3 years -20°C powder
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