LGE-899
LGE-899 (M48) is the primary active metabolite of the hedgehog pathway inhibitor Sonidegib, characterized by a significantly extended Tmax of approximately 60 hours. This metabolite is a valuable research tool for investigating the pharmacokinetics and sustained pharmacodynamic effects of Sonidegib in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1221722-10-6
Product Name Alternative
DrugMetabolite, Drug Metabolite, circulating metabolite of Sonidegib, inhibit, Inhibitor, LGE 899, LGE899, LGE-899, hedgehog pathway inhibitor, Sonidegib metabolite M48, Sonidegib metabolite M-48, Sonidegib metabolite M 48
Field of Research
Metabolism Research
Purity
99.77% (May vary between batches)
Solubility
DMSO:10 mg/mL (33.76 mM)
Smiles
Cc1c (cccc1-c1ccc (OC (F) (F) F) cc1) C (O) =O
Molecular Formula
C15H11F3O3
Molecular Weight
296.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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