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BI-4020

Product Specifications

CAS Number

2664214-60-0

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1CCCOC2=C (C=N[N]2C) C3=NC (=CC (=C3) C (=O) N=C4NC5=C (C=C (CN6CCN (C) CC6) C=C5) N4C1) C

Molecular Formula

C30H38N8O2

Additionnal Information

BI-4020 is an orally active, non-covalent EGFR inhibitor with IC50 of 0.6 nM and 0.2 nM for EGFRdel19 T790M C797S as biomarker potency and anti-proliferation potency in BaF3 cells, respectively.

Storage Conditions

3 years -20°C powder

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