XY-52
Product Specifications
Target
Others, Interleukin
Related Pathways
Others, Immunology/Inflammation
Bioactivity
XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasma sST2 and IFNγ biomarkers in a graft versus host disease (GVHD) mouse model [1].
Smiles
CC1=CC([N+]([O-])=O)=CC=C1C2=CC=C(CN3C(C4=CC=CC(N5CC(CC6)NC6C5)=C4)CCC3)N2CC
Molecular Formula
C30H37N5O2
Molecular Weight
499.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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