Takinib
Product Specifications
CAS Number
1111556-37-6
Synonyms
EDHS-206
Target
TAK1
Applications
MAPK
Smiles
CCCN1C2=CC=CC=C2N=C1NC (=O) C3=CC=CC (=C3) C (=O) N
Molecular Formula
C18H18N4O2
Additionnal Information
Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.
Storage Conditions
2 years -80 in solvent
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